Organooxygen compounds
Medchemexpress LLC Pholedrine (hydrochloride) | 877-86-1 | 99.6% | 10 MG
Pholedrine hydrochloride is the hydrochloride salt of pholedrine, an indirectly acting sympathomimetic amine used in research on adrenergic receptors and cardiovascular responses. It is supplied as a solid research chemical with recommended storage at 4°C (sealed), and solution storage at -80°C for long-term preservation.
- Hydrochloride salt form for improved stability.
- Used to study adrenergic receptor activity and cardiovascular effects.
- Available in small milligram pack sizes suitable for research, e.g. 10 MG.
- Molecular formula C10H16ClNO; molecular weight 201.69 g/mol.
- Recommended storage: 4°C sealed; in solution store at -80°C for long-term.
Medchemexpress LLC VU0357017 hydrochloride | 1135242-13-5 | MFCD17215959 | 99.9% | 369.89 | C18H28ClN3O3 | 10 MG
VU0357017 hydrochloride is a brain-penetrant, selective allosteric agonist of the M1 muscarinic acetylcholine receptor used as a research tool to probe M1 receptor pharmacology and signaling. Supplied as the hydrochloride salt, the compound is characterized by a defined molecular weight and high reported purity.
- Potent M1 allosteric agonist with reported EC50 ≈ 477 nM.
- Brain-penetrant small molecule suitable for in vitro and in vivo studies.
- High chemical purity as provided by manufacturer.
- Provided as a hydrochloride salt for improved solubility.
- Available in small research pack sizes for laboratory use.
eMolecules 485-47-2 | Ninhydrin | Oakwood Chemical | MFCD00003791 | 178.143 | C9H6O4 | 98.000 | OC1(O)C(=O)c2ccccc2C1=O | 25g | 537717968
Ninhydrin | Oakwood Chemical | 485-47-2 | MFCD00003791 | 178.143 | C9H6O4 | 98.000 | OC1(O)C(=O)c2ccccc2C1=O | 25g | 537717968
eMolecules 485-47-2 | Ninhydrin | Oakwood Chemical | MFCD00003791 | 178.143 | C9H6O4 | 98.000 | OC1(O)C(=O)c2ccccc2C1=O | 10g | 537717967
Ninhydrin | Oakwood Chemical | 485-47-2 | MFCD00003791 | 178.143 | C9H6O4 | 98.000 | OC1(O)C(=O)c2ccccc2C1=O | 10g | 537717967
eMolecules 51285-26-8 | Picolinimidamide hydrochloride | Ambeed | MFCD00052271 | 157.600 | C6H8ClN3 | 97.000 | Cl.NC(=N)c1ccccn1 | 25g | 490512024
Picolinimidamide hydrochloride | Ambeed | 51285-26-8 | MFCD00052271 | 157.600 | C6H8ClN3 | 97.000 | Cl.NC(=N)c1ccccn1 | 25g | 490512024
Medchemexpress LLC Viloxazine hydrochloride | 35604-67-2 | MFCD00661100 | >95.0% | 273.76 | C13H20ClNO3 | 10MG
Viloxazine hydrochloride is the hydrochloride salt of viloxazine supplied for research use as a norepinephrine transporter inhibitor and serotonin receptor modulator. It is provided as a solid for laboratory assays, method development, and biochemical screening. Typical chemical identifiers include CAS 35604-67-2, molecular weight 273.76, and formula C13H20ClNO3.
Medchemexpress LLC Fadrozole hydrochloride | 102676-31-3 | 99.9% | C14H14ClN3 | 100 MG
Fadrozole hydrochloride (CGS 16949A) is a potent, selective, and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM. Intended for research use only, this compound effectively inhibits estrogen and progesterone production. It has demonstrated efficacy in preventing the development of various spontaneous neoplasms and reducing parasite burden in animal models.
- Potent, selective, and nonsteroidal aromatase inhibitor
- Inhibits estrogen production in hamster ovarian slices
- Inhibits progesterone production
- Prevents development of benign and malignant spontaneous mammary neoplasms
- Reduces incidence of spontaneous hepatocellular tumors
- Reduces parasite burden in male and female mice
Medchemexpress LLC Emixustat hydrochloride | 1141934-97-5 | 99.3% | 299.84 | 50 MG
Emixustat hydrochloride (ACU-4429) is an orally active RPE65 inhibitor with an IC50 value of 4.4 nM. It functions as a visual cycle modulator by inhibiting retinol isomerization. This compound shows potential for research into vision disorders such as age-related macular degeneration (AMD).
- Reduces the production of 11-cis-retinol in a concentration-dependent manner, thereby inhibiting RPE65 activity.
- Reduces the conductance of retinal cation channels after dark adaptation in rats.
- Dose-dependently reduces retinal neovascularization in an Oxygen-Induced Retinopathy (OIR) mouse model.
Medchemexpress LLC Clemizole hydrochloride | 1163-36-6 | 99.99% | 362.30 | 1 ML
Clemizole hydrochloride is an H1 histamine receptor antagonist that substantially inhibits HCV replication. It also acts as an inhibitor of the TRPC5 channel. The IC50 for RNA binding by NS4B is 24 nM, and its EC50 for viral replication is 8 μM.
- Inhibits HCV RNA replication
- Suppresses NS4B's RNA binding with low host cell toxicity
- Blocks TRPC5 currents and Ca2+ entry
- Exhibits selectivity for TRPC5 over TRPC4β, TRPC3, and TRPC6
Medchemexpress LLC Sultopride hydrochloride | 23694-17-9 | 99.9% | 390.93 | 50 MG
Sultopride hydrochloride is a selective antagonist of the dopamine D2 receptor. It has shown increased levels of DOPAC and HVA in the striatum, nucleus accumbens, and medial prefrontal cortex in treated rats.
- Acts as a selective antagonist of dopamine D2 receptor.
- Demonstrates high purity of 99.92%.
- Soluble in water and DMSO for in vitro applications.
- Suitable for in vivo studies with protocol for PBS solubility.
- Available in solid form, white to off-white in appearance.
- Stored at 4°C, sealed, away from moisture.
Medchemexpress LLC Drofenine hydrochloride | 548-66-3 | 98.1% | 1 ML
Drofenine hydrochloride is a potent competitive cholinesterase inhibitor. It acts as a BChE inhibitor with a Ki value of 3 μM and is intended for research use only.
- Potent competitive cholinesterase inhibitor
- BChE inhibitor
- Ki value of 3 μM
- Suitable for research use
Medchemexpress LLC Tocainide hydrochloride | 71395-14-7 | 99.5% | 1 ML
Tocainide hydrochloride is a sodium channel blocker that blocks sodium channels in pain-producing foci in nerve membranes. It is a primary amine analog of lidocaine and can be used for the treatment of tinnitus.
- Suppresses ventricular ectopic activity.
- Suitable for laboratory centrifugation and storage.
Medchemexpress LLC Fingolimod hydrochloride | 162359-56-0 | 99.9% | 1 ML
Fingolimod hydrochloride (FTY720) is a sphingosine 1-phosphate (S1P) receptor modulator supplied as a 10 mM solution in DMSO for research use, suitable for cellular and pharmacology studies of S1P signaling.
- 10 mM solution in DMSO, 1 mL vial.
- High purity (99.94%).
- Molecular weight 343.93 g/mol.
- CAS number 162359-56-0.
- Store in solvent at -80°C (up to 6 months) or -20°C (up to 1 month); solid at 4°C.
Medchemexpress LLC SRI-011381 hydrochloride | 2070014-88-7 | 99.6% | 365.94 g/mol | C20H32ClN3O | 50 MG
SRI-011381 hydrochloride is an orally active TGF-β signaling agonist used in research to modulate TGF-β/Smad pathways and investigate neuroprotective mechanisms. It shows activity in cell-based assays and animal studies, including promotion of fibroblast proliferation and mitigation of inflammation-related neuronal loss.
- Orally active TGF-β signaling agonist.
- Demonstrates neuroprotective effects in vitro and in vivo.
- Promotes fibroblast proliferation and increases TGF-β1, NALP3, collagen-1, and α-SMA expression.
- Shown to reduce inflammatory infiltration and alleviate neuronal loss in animal models.
- Supplied as a solid with high purity and defined storage recommendations for research use.
Medchemexpress LLC VU0453379 hydrochloride | 99.0% | 471.03 | 1 ML
VU0453379 hydrochloride is a highly selective and central nervous system (CNS) penetrant positive allosteric modulator (PAM) of glucagon-like peptide-1R (GLP-1R). It exhibits an EC50 of 1.3 μM.
- Highly selective positive allosteric modulator.
- Central nervous system (CNS) penetrant.
- Modulates glucagon-like peptide-1R (GLP-1R).
- Demonstrates an EC50 of 1.3 μM.